type ii topoisomerase enzymes
跳到 Topoisomerase II as a genotoxic enzyme - Topoisomerase II-DNA cleavage complexes are transient in ... complexes falls too low (i.e., enzyme activity is lowered), ... linked to the initiation of specific types of acute leukemias. , Type II enzymes (e.g. topoisomerase (topo) II and DNA gyrase) are known to operate by a strand-passage mechanism in which a segment of ...
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 type ii topoisomerase enzymes 相關參考資料
DNA topoisomerase II, eukaryotic-type (IPR001154) < InterPro ...
DNA topoisomerases are divided into two classes: type I enzymes (EC:5.99.1.2; topoisomerases I, III and V) break single-strand DNA, and type II enzymes ... http://www.ebi.ac.uk DNA Topoisomerase II, Genotoxicity, and Cancer - NCBI - NIH
跳到 Topoisomerase II as a genotoxic enzyme - Topoisomerase II-DNA cleavage complexes are transient in ... complexes falls too low (i.e., enzyme activity is lowered), ... linked to the initiation of sp... https://www.ncbi.nlm.nih.gov How do type II topoisomerases use ATP hydrolysis to simplify ...
Type II enzymes (e.g. topoisomerase (topo) II and DNA gyrase) are known to operate by a strand-passage mechanism in which a segment of ... https://www.ncbi.nlm.nih.gov Structure and function of type II DNA topoisomerases.
Conditional expression of wild-type topoisomerase II complements a mutant enzyme in mammalian cells. J Biol Chem. 1993 Jul 5;268(19):13844–13849. https://www.ncbi.nlm.nih.gov The ancestral role of ATP hydrolysis in type II topoisomerases ...
A long-standing puzzle has been to understand why the majority of type II enzymes consume ATP to support reactions that do not require a net ... https://www.ncbi.nlm.nih.gov The Use of Divalent Metal Ions by Type II Topoisomerases
Type II topoisomerases are essential enzymes that regulate DNA under- and overwinding and remove knots and tangles from the genetic material. In order to ... https://www.ncbi.nlm.nih.gov Topoisomerase - Wikipedia
跳到 Function - The unlinking of catenanes is performed by type IIA topoisomerases, ... to their corresponding enzymatic reaction catalyzed by topoisomerases. https://en.wikipedia.org Type II Topoisomerase - an overview | ScienceDirect Topics
This enzyme is a single subunit protein and functions in the form of a dimer. All known type II topoisomerases are adenosine triphosphate (ATP)-dependent. https://www.sciencedirect.com Type II topoisomerase - Wikipedia
https://en.wikipedia.org Type II topoisomerases--inhibitors, repair mechanisms and ...
Type II topoisomerases are ubiquitous enzymes that play an essential role in the control of replicative DNA synthesis and share structural and ... https://www.ncbi.nlm.nih.gov |