topoisomerase ii inhibitor

2018年6月5日 — Amsacrine (5) and ametantrone (7) are two identified topo II poisons that have a broad spectrum of antitumo...

topoisomerase ii inhibitor

2018年6月5日 — Amsacrine (5) and ametantrone (7) are two identified topo II poisons that have a broad spectrum of antitumor activities. Acting as excellent DNA ... ,2019年10月8日 — D., and includes the design, synthesis, and evaluation of new DNA topoisomerase II inhibitors as potential anticancer drugs. Biography. Nace ...

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topoisomerase ii inhibitor 相關參考資料
Catalytic inhibitors of DNA topoisomerase II - ScienceDirect

In recent years a diverse group of drugs has been reported which inhibit topoisomerase II activity but unlike the classical topoisomerase II poisons they lack the ...

https://www.sciencedirect.com

Discovery of Novel Topoisomerase II Inhibitors by Medicinal ...

2018年6月5日 — Amsacrine (5) and ametantrone (7) are two identified topo II poisons that have a broad spectrum of antitumor activities. Acting as excellent DNA ...

https://pubs.acs.org

Dual Inhibitors of Human DNA Topoisomerase II and Other ...

2019年10月8日 — D., and includes the design, synthesis, and evaluation of new DNA topoisomerase II inhibitors as potential anticancer drugs. Biography. Nace ...

https://pubs.acs.org

Resveratrol: A novel type of topoisomerase II inhibitor - PubMed

2017年12月22日 — Interestingly, resveratrol is chemically similar to ICRF-187, a clinically approved chemotherapeutic that stabilizes an ATP-dependent dimerization ...

https://pubmed.ncbi.nlm.nih.go

Targeting DNA topoisomerase II in cancer chemotherapy - NCBI

跳到 Inhibition of Top2 activity by anti-cancer agents — Catalytic inhibitors of topoisomerase II. Several classes of compounds have been described that target ...

https://www.ncbi.nlm.nih.gov

Topoisomerase II inhibitors - ScienceDirect

Currently available topoisomerase I inhibitors are irinotecan (CPT-11) and topotecan. FDA-approved topoisomerase II inhibitors are etoposide, teniposide, ...

https://www.sciencedirect.com

Topoisomerase II Inhibitors | DrugBank Online

Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic ...

https://go.drugbank.com

Topoisomerase Inhibitor - an overview | ScienceDirect Topics

Topotecan, a topoisomerase I inhibitor, has shown activity as a single agent in recurrent disease and remains the only FDA-approved agent for use in the second ...

https://www.sciencedirect.com

Topoisomerase inhibitor - Wikipedia

跳到 Type I topoisomerase inhibitors — Topoisomerase inhibitors are chemical compounds that block the action of topoisomerases (topoisomerase I and II), ...

https://en.wikipedia.org

Topoisomerase Inhibitors - Chemotherapy for Cancer Treatment

Both topoisomerase I and II inhibitors bind to the topoisomerase molecule. This makes the enzyme nonfunctional by blocking the ability of the topoisomerase to ...

https://chemoth.com