wnt pathway apc

The canonical Wnt signalling pathway and its APC partner in colon cancer development. Jean Schneikert and Jürgen Behrens...

wnt pathway apc

The canonical Wnt signalling pathway and its APC partner in colon cancer development. Jean Schneikert and Jürgen Behrens. Additional article information. The ... , We conclude that increased WNT signaling is important in the transition to malignancy in the serrated pathway but that APC mutation is less ...

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wnt pathway apc 相關參考資料
Apc, wnt signaling pathway regulator - Wikipedia

APC, WNT signaling pathway regulator is a protein that in humans is encoded by the APC gene.

https://en.wikipedia.org

The canonical Wnt signalling pathway and its APC partner in ...

The canonical Wnt signalling pathway and its APC partner in colon cancer development. Jean Schneikert and Jürgen Behrens. Additional article information. The ...

https://www.ncbi.nlm.nih.gov

The role of APC in WNT pathway activation in serrated ...

We conclude that increased WNT signaling is important in the transition to malignancy in the serrated pathway but that APC mutation is less ...

https://www.nature.com

Wnt β-Catenin Signaling | Cell Signaling Technology

E-cadherin, APC, R-spondin and Axin mutations have also been documented in tumor samples, underscoring the deregulation of this pathway in cancer. Wnt ...

https://www.cellsignal.com

Wnt signaling and colon carcinogenesis: Beyond APC - NCBI

Activation of the Wnt signaling pathway via mutation of the adenomatous polyposis coli gene (APC) is a critical event in the development of ...

https://www.ncbi.nlm.nih.gov

Wnt signaling in cancer | Oncogene - Nature

The APC gene was found to interact with β-catenin and loss of function of APC resulted in overactive T-cell factor (TCF)4/β-catenin signaling.

https://www.nature.com

Wnt signaling pathway - Wikipedia

Axin, GSK and APC form a "destruction complex," and β-Cat is destroyed. Foundation[edit]. Wnt signaling begins when a Wnt protein binds to the N- ...

https://en.wikipedia.org

Wntβ-catenin signaling: components, mechanisms, and ...

Another paradoxical observation is that APC has a positive function in physiological and ectopic Wg/Wnt signaling through the promotion of Axin degradation (Lee ...

https://www.ncbi.nlm.nih.gov

Wnt信號通路- 維基百科,自由的百科全書 - Wikipedia

現在已鑑別出三種Wnt信號通路:經典Wnt通路(canonical Wnt pathway)、非 ... 與APC蛋白。axin/GSK-3/APC 複合體可促進細胞內信號分子β-catenin的降解。

https://zh.wikipedia.org