tumor suppressor gene example
跳到 Examples — Examples[edit] · Retinoblastoma protein (pRb). pRb was the first tumor-suppressor protein discovered in human retinoblastoma; however, ... ,Several tumor suppressor genes encode transcriptional regulatory proteins. A good example is provided by the product of WT1, which is frequently inactivated in Wilms' tumors (a childhood kidney tumor). The WT1 protein is a repressor that appears to su
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 tumor suppressor gene example 相關參考資料
Tumor Suppressor Genes: Function and Role in Cancer
https://www.verywellhealth.com Tumor suppressor gene - Wikipedia
跳到 Examples — Examples[edit] · Retinoblastoma protein (pRb). pRb was the first tumor-suppressor protein discovered in human retinoblastoma; however, ... https://en.wikipedia.org Tumor Suppressor Genes - The Cell - NCBI Bookshelf
Several tumor suppressor genes encode transcriptional regulatory proteins. A good example is provided by the product of WT1, which is frequently inactivated in Wilms' tumors (a childhood kidney tu... https://www.ncbi.nlm.nih.gov Proto-Oncogenes and Tumor-Suppressor Genes - Molecular ...
In later sections, we discuss specific examples of precisely how oncogenic mutations cause the abnormalities characteristic of tumor cells. Certain viruses also ... https://www.ncbi.nlm.nih.gov Oncogenes and tumor suppressor genes | American Cancer ...
2014年6月25日 — Tumor suppressor genes are normal genes that slow down cell ... For example, abnormalities of the TP53 gene (which codes for the p53 ... https://www.cancer.org Tumor Suppressor Genes - an overview | ScienceDirect Topics
Examples include BUB1, BUBR1, TGF-βRII, Axin, DPC4, p300, and PPARγ. The most frequent mechanism of inactivation of the second allele of a tumor suppressor gene is allelic deletion, and therefore loss... https://www.sciencedirect.com Tumor Suppressor Gene - an overview | ScienceDirect Topics
One can see from these latter examples that tumor suppressor genes act on (negatively regulate) oncogenes and different signal transduction pathways ... https://www.sciencedirect.com |