topology genetics

由 G Cavalli 著作 · 2013 · 被引用 409 次 — A fundamental property of genomes is their topological ... precise nature of geno...

topology genetics

由 G Cavalli 著作 · 2013 · 被引用 409 次 — A fundamental property of genomes is their topological ... precise nature of genome topology and its regulatory functions in gene expression ...,由 Y Ghavi-Helm 著作 · 2019 · 被引用 127 次 — The functional impact of these genetic perturbations on genome topology and gene expression was assessed in cis in heterozygote embryos, using ...

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topology genetics 相關參考資料
Using topology to tame the complex biochemistry of genetic ...

由 M Thattai 著作 · 2013 · 被引用 7 次 — Genes encode proteins, which in turn carry out the processes required for the maintenance of cellular life. During the process of gene expression, the genetic ...

https://www.ncbi.nlm.nih.gov

Functional implications of genome topology - NCBI - NIH

由 G Cavalli 著作 · 2013 · 被引用 409 次 — A fundamental property of genomes is their topological ... precise nature of genome topology and its regulatory functions in gene expression ...

https://www.ncbi.nlm.nih.gov

Highly rearranged chromosomes reveal uncoupling between ...

由 Y Ghavi-Helm 著作 · 2019 · 被引用 127 次 — The functional impact of these genetic perturbations on genome topology and gene expression was assessed in cis in heterozygote embryos, using ...

https://www.nature.com

Dynamic interplay between enhancer–promoter topology and ...

由 H Chen 著作 · 2018 · 被引用 176 次 — A long-standing question in gene regulation is how remote enhancers communicate with their target promoters, and specifically how chromatin ...

https://www.nature.com

Modeling regulatory network topology improves genome-wide ...

由 X Zhu 著作 · 2021 · 被引用 1 次 — Integration of GWAS with gene regulatory networks addresses both issues by aggregating weak genetic signals within regulatory programs. Here we ...

https://www.nature.com

Transcription factors orchestrate dynamic interplay between ...

由 R Stadhouders 著作 · 2018 · 被引用 184 次 — Here, we used this system to integrate time-resolved changes in genome topology with gene expression, TF binding and chromatin-state ...

https://www.nature.com

Topology of genes and nontranscribed sequences in human ...

由 MO Scheuermann 著作 · 2004 · 被引用 110 次 — Knowledge about the functional impact of the topological organization of DNA sequences within interphase chromosome territories is still sparse.

https://pubmed.ncbi.nlm.nih.go

Dynamic interplay between enhancer-promoter topology and ...

由 H Chen 著作 · 2018 · 被引用 176 次 — A long-standing question in gene regulation is how remote enhancers communicate with their target promoters, and specifically how chromatin ...

https://pubmed.ncbi.nlm.nih.go

Conservation and functional significance of gene topology in ...

由 N Chen 著作 · 2006 · 被引用 51 次 — Conservation and functional significance of gene topology in the genome of Caenorhabditis elegans. Genome Res. 2006 May;16(5):606-17. doi: ...

https://pubmed.ncbi.nlm.nih.go