sclerostin
由 BL Langdahl 著作 · 被引用 6 次 — Sclerostin, which is primarily produced by the osteocytes, inhibits the canonical Wnt pathway and thereby the osteoblasts and stimulates RANKL ... ,由 J Delgado-Calle 著作 · 2017 · 被引用 219 次 — A potent antagonist of Wnt signaling secreted by osteocytes is sclerostin, a protein encoded by the Sost gene primarily expressed by mature ...
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 sclerostin 相關參考資料
50964 - Gene ResultSOST sclerostin [ (human)] - NCBI
2021年11月28日 — Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential ... https://www.ncbi.nlm.nih.gov Cardiovascular Safety and Sclerostin Inhibition - PubMed
由 BL Langdahl 著作 · 被引用 6 次 — Sclerostin, which is primarily produced by the osteocytes, inhibits the canonical Wnt pathway and thereby the osteoblasts and stimulates RANKL ... https://pubmed.ncbi.nlm.nih.go Role and mechanism of action of Sclerostin in bone - NCBI
由 J Delgado-Calle 著作 · 2017 · 被引用 219 次 — A potent antagonist of Wnt signaling secreted by osteocytes is sclerostin, a protein encoded by the Sost gene primarily expressed by mature ... https://www.ncbi.nlm.nih.gov Role and mechanism of action of sclerostin in bone - PubMed
由 J Delgado-Calle 著作 · 2017 · 被引用 220 次 — After discovering that lack of Sost/sclerostin expression is the cause of the high bone mass human syndromes Van Buchem disease and sclerosteosis, ... https://pubmed.ncbi.nlm.nih.go Role of sclerostin in bone and cartilage and its potential as a ...
由 EM Lewiecki 著作 · 2014 · 被引用 124 次 — Sclerostin is a small protein expressed by the SOST gene in osteocytes, bone cells that respond to mechanical stress applied to the skeleton and appear to .... https://www.ncbi.nlm.nih.gov Sclerostin - an overview | ScienceDirect Topics
Sclerostin, a product of the SOST gene primarily expressed by osteocytes, is a secreted glycoprotein that functions as a key negative regulator of bone ... https://www.sciencedirect.com Sclerostin - Wikipedia
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected ... https://en.wikipedia.org Sclerostin: from bench to bedside - PubMed
由 S Tanaka 著作 · 被引用 14 次 — ... Wnt signaling pathways in maintaining skeletal homeostasis. The SOST gene, which encodes sclerostin, a member of Dan family glycoprote … https://pubmed.ncbi.nlm.nih.go Sclerostin: Intracellular mechanisms of action and its role in ...
由 B Pietrzyk 著作 · 2017 · 被引用 44 次 — Sclerostin is a glycoprotein involved in the regulation of bone metabolism, exclusively secreted by osteocytes. It affects the activity of bone ... https://pubmed.ncbi.nlm.nih.go |