p53 oncogene or tumor suppressor
It was initially presumed to be an oncogene due to the use of mutated cDNA following purification of tumor cell mRNA. Its role as a tumor suppressor gene was ... ,The p53 protein was bound to the major oncogenic protein of SV40, strongly ... This was the result expected for a tumor suppressor gene, not an oncogene.
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Do Mutations Turn p53 into an Oncogene? - NCBI - NIH
The key role of p53 as a tumor suppressor became clear when it was realized that this gene is mutated in ... https://www.ncbi.nlm.nih.gov p53 - Wikipedia
It was initially presumed to be an oncogene due to the use of mutated cDNA following purification of tumor cell mRNA. Its role as a tumor suppressor gene was ... https://en.wikipedia.org p53, Cancer | Learn Science at Scitable - Nature
The p53 protein was bound to the major oncogenic protein of SV40, strongly ... This was the result expected for a tumor suppressor gene, not an oncogene. https://www.nature.com p53: not just a tumor suppressor | Journal of Molecular Cell ...
2019年8月20日 — Thus, after being considered an oncogene for several years, p53 finally was canonized as a star tumor suppressor. But what about the old ... https://academic.oup.com p53: Oncogene, Tumor Suppressor, or Both? | SpringerLink
p53: Oncogene, Tumor Suppressor, or Both? Authors; Authors and affiliations. W. Deppert. https://link.springer.com TP53: an oncogene in disguise - NCBI - NIH
2015年5月29日 — The standard classification used to define the various cancer genes confines tumor protein p53 (TP53) to the role of a tumor suppressor gene. https://www.ncbi.nlm.nih.gov TP53: an oncogene in disguise - PubMed
The standard classification used to define the various cancer genes confines tumor protein p53 (TP53) to the role of a tumor suppressor gene. However, it is now ... https://pubmed.ncbi.nlm.nih.go TP53: an oncogene in disguise | Cell Death & Differentiation
https://www.nature.com Tumor Suppressive Functions of p53 - NCBI - NIH
Hence, p53 can be activated in response to DNA damage, oncogene ... Importantly, these p53 tumor suppressor functions are context-dependent and may be ... https://www.ncbi.nlm.nih.gov 後天基因:致癌基因(oncogene)還是抑癌基因(tumor ... - 基因叔叔
2016年9月13日 — 後天基因:致癌基因(oncogene)還是抑癌基因(tumor suppressor gene)? ... 的確也已經證實p53突變所導致的相關癌症,其中有大腸癌、乳癌、 ... https://unclegene6666.pixnet.n |