oncogene p53
Therefore, understanding the structure and functions of oncogenic p53 mutants may lead to more potent reactivation modalities or to the ability ...,Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), .... Oncogenes also stimulate p53 activation, mediated by the protein p14ARF. In unstressed cells, p53 levels are kept low through a continuous degradation of ...
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 oncogene p53 相關參考資料
Mutant p53: an oncogenic transcription factor | Oncogene
Unlike other tumor-suppressor genes, p53 is inactivated by missense ... loss of wild-type p53 tumor suppressor activity, but gain new oncogenic ... https://www.nature.com Oncogenic Mutations of the p53 Tumor Suppressor: The ...
Therefore, understanding the structure and functions of oncogenic p53 mutants may lead to more potent reactivation modalities or to the ability ... https://cancerres.aacrjournals p53 - Wikipedia
Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), .... Oncogenes also stimulate p53 activation, mediated by the protein p14ARF. In unstressed cells, p53 levels are kept ... https://en.wikipedia.org p53, Cancer | Learn Science at Scitable - Nature
A variety of studies carried out with the protein, and later with the gene encoding p53, indicated that it was an oncogene (Eliyahu et al. 1984, Jenkins et al. 1984 ... https://www.nature.com p53: oncogene or anti-oncogene? - Genes & Development
the retinoblastoma (Rb) gene. Like p53, the retinoblas- toma protein pl05-Rb is physically complexed to the oncogene products of different groups of DNA tumor ... http://genesdev.cshlp.org p53: Oncogene, Tumor Suppressor, or Both? | SpringerLink
Cytogenetic [34] and molecular genetic [25] analyses have identified tumor-specific genomic changes, thus providing accumulating evidence for a genetic ... https://link.springer.com The cellular oncogene p53 can be activated by mutagenesis ...
Cells immortalized by one of these mutants are refractory to subsequent transformation by a ras oncogene, indicating that cellular ... https://www.nature.com TP53: an oncogene in disguise - NCBI
How does the diversity of oncogenic p53 variants contribute to the heterogeneity of the malignant phenotype? What is the contribution of p53 ... https://www.ncbi.nlm.nih.gov TP53: an oncogene in disguise | Cell Death & Differentiation
However, it is now an indisputable fact that many p53 mutants act as oncogenic proteins. This statement is based on multiple arguments ... https://www.nature.com 後天基因：致癌基因(oncogene)還是抑癌基因(tumor suppressor ...
致癌基因(Oncogene) 致癌基因(Oncogene)是一種可誘發細胞不正常發育 ... 抑制基因，透過基因轉錄及轉譯出來具有功能性的蛋白質為p53。p53是 ... https://unclegene6666.pixnet.n |