cefazolin time or concentration dependent
由 KA Cholewka 著作 · 1999 · 被引用 3 次 — Dependence of the bactericidal effect of β-lactam antibiotics in general, and cephalosporins in particular, on antibiotic concentration, time of exposure or ... ,由 BI Naik 著作 · 2017 · 被引用 33 次 — Cefazolin is a time-dependent antibiotic that demonstrates maximal efficacy when ... The observed mean (sd) total and unbound cefazolin concentration–time ...
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 cefazolin time or concentration dependent 相關參考資料
#PharmToExamTable: What is the evidence for continuous ...
由 JR Marcelin 著作 — Due to time-dependent pharmacodynamics, the efficacy of cephalosporins is associated with time above the minimum inhibitory concentration (T>MIC ... https://blog.unmc.edu Cephalosporin clinical concentration–time profile modelling ...
由 KA Cholewka 著作 · 1999 · 被引用 3 次 — Dependence of the bactericidal effect of β-lactam antibiotics in general, and cephalosporins in particular, on antibiotic concentration, time of exposure or .... https://academic.oup.com Comparative total and unbound pharmacokinetics of ...
由 BI Naik 著作 · 2017 · 被引用 33 次 — Cefazolin is a time-dependent antibiotic that demonstrates maximal efficacy when ... The observed mean (sd) total and unbound cefazolin concentration–time ... https://www.sciencedirect.com Comparative total and unbound pharmacokinetics of cefazolin ...
Cefazolin is a time-dependent antibiotic that demonstrates maximal efficacy when serum concentrations are above the minimal inhibitory concentration (MIC; ƒT>MIC). https://www.bjanaesthesia.org. Excessive unbound cefazolin concentrations in critically ill ...
由 H Booke 著作 · 2021 · 被引用 3 次 — In this setting, cefazolin has a retention time of 3.16 min (see Fig. ... As PK of cefazolin is mainly dependent on renal function and CRRT ... https://www.nature.com Plasma and Tissue Pharmacokinetics of Cefazolin in ...
由 A Douglas 著作 · 2011 · 被引用 83 次 — The median cross-clamp time of 54 min (IQR, 48 to 66 min) was not dependent upon the overall duration of surgery, which had an IQR of 2.6 to 3.2 h. https://www.ncbi.nlm.nih.gov Population Pharmacokinetic Study of Cefazolin Used ...
由 P Cagnardi 著作 · 被引用 12 次 — Cephalosporins like all beta-lactams have time-dependent killing activity; therefore, antibiotic plasma concentrations should be kept above the. https://air.unimi.it Safety and Efficacy of Cefazolin Sodium in the Management of ...
由 T Kusaba 著作 · 2009 · 被引用 40 次 — In these case reports, cefazolin was administered 3 to 8 g/day for several days despite of severe renal impairment (at least, more than 7.2 mg/ ... https://journals.sagepub.com Time-Dependent vs. Concentration-Dependent Killing
Interstitial fluid drug concentrations are proportional to and in rapid equilibrium with blood and, therefore, the concentration of the antibiotic correlates ... http://www.antimicrobe.org Tissue Pharmacokinetics of Cefazolin in Patients with ...
由 AA Bhalodi 著作 · 2013 · 被引用 28 次 — Similar to other cephalosporins, cefazolin displays time-dependent killing, and therefore, the PD driver of efficacy is the amount of time that free-drug ... https://www.ncbi.nlm.nih.gov |