beta catenin degradation
Wnt regulation of β-catenin degradation is essential for development and carcinogenesis. ... Depletion of CKIα inhibits β-catenin phosphorylation and degradation and causes abnormal embryogenesis associated with excessive Wnt/β-catenin signaling., Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin ...
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 beta catenin degradation 相關參考資料
Control of beta-catenin phosphorylationdegradation by a dual-kinase ...
Wnt regulation of beta-catenin degradation is essential for development and carcinogenesis. beta-catenin degradation is initiated upon ... https://www.ncbi.nlm.nih.gov Control of β-Catenin PhosphorylationDegradation by a Dual-Kinase ...
Wnt regulation of β-catenin degradation is essential for development and carcinogenesis. ... Depletion of CKIα inhibits β-catenin phosphorylation and degradation and causes abnormal embryogenesis ass... https://www.sciencedirect.com Molecular association between beta-catenin degradation complex and ...
Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin ... https://www.ncbi.nlm.nih.gov The regulation of β-catenin activity and function in cancer: therapeutic ...
This leads to the ubiquitylation and proteasomal degradation of β-catenin. Upon Wnt activation or genetic mutations of Wnt components, β-catenin accumulates ... https://www.ncbi.nlm.nih.gov The β-Catenin Destruction Complex - NCBI - NIH
跳到 β-CATENIN DESTRUCTION OCCURS VIA PROTEASOMAL ... - The Wnt/β-catenin pathway is highly regulated to insure the correct temporal and spatial activation of its target genes. ... Ubiquitinated β-cate... https://www.ncbi.nlm.nih.gov The β-catenin destruction complex. - NCBI - NIH
In the absence of a Wnt stimulus, the transcriptional coactivator β-catenin is degraded by a multiprotein "destruction complex" that includes the ... https://www.ncbi.nlm.nih.gov Wnt signaling through inhibition of β-catenin degradation in an ... - NCBI
Cell. 2012 Jun 8;149(6):1245-56. doi: 10.1016/j.cell.2012.05.002. Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex. Li VS(1) ... https://www.ncbi.nlm.nih.gov Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact ...
Degradation of cytosolic β-catenin by the APC/Axin1 destruction complex represents the key regulated step of the Wnt pathway. It is incompletely understood how the Axin1 complex exerts its Wnt-regula... https://www.sciencedirect.com |