Ranolazine mechanism of action
由 C Marx 著作 · 2006 · 被引用 8 次 — The proposed ranolazine mechanism of action is the inhibition of pathologic increases in late Na+ current induced during myocardial ischemia ... ,由 G Hasenfuss 著作 · 2008 · 被引用 82 次 — Most specifically, ranolazine has been shown to reverse the sustained rise in diastolic and systolic calcium caused by a well-known enhancer of ...
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 Ranolazine mechanism of action 相關參考資料
Late Sodium Current Blocker (Ranolazine) - Cardiovascular ...
Ranolazine represents a new class of antianginal drugs. It blocks late inward sodium currents in cardiomyocytes. In the ischemic myocardium, late inward sodium ... https://www.cvpharmacology.com Mechanism of Action of Ranolazine | Cardiology - JAMA ...
由 C Marx 著作 · 2006 · 被引用 8 次 — The proposed ranolazine mechanism of action is the inhibition of pathologic increases in late Na+ current induced during myocardial ischemia ... https://jamanetwork.com Mechanism of action of the new anti-ischemia drug ranolazine
由 G Hasenfuss 著作 · 2008 · 被引用 82 次 — Most specifically, ranolazine has been shown to reverse the sustained rise in diastolic and systolic calcium caused by a well-known enhancer of ... https://www.ncbi.nlm.nih.gov Ranolazine - NCBI
由 BM Reddy 著作 · 2010 · 被引用 41 次 — Ranolazine, a piperazine derivative, is a new antianginal drug with a novel mechanism of action that appears to offer freedom from most adverse hemodynamic ... https://www.ncbi.nlm.nih.gov Ranolazine - StatPearls - NCBI Bookshelf
Mechanism of Action · 由 M Reed 著作 · 2020 · 被引用 4 次 — This activity outlines the indications, mechanism of action, methods of administration, important adverse effects, contraindications, ... https://www.ncbi.nlm.nih.gov Ranolazine - Wikipedia
https://en.wikipedia.org Ranolazine Article - StatPearls
2021年10月25日 — Mechanism of Action ... At higher concentrations, ranolazine inhibits rapid delayed rectifier potassium current, thus delaying action potential ... https://www.statpearls.com Ranolazine: A Contemporary Review - AHA Journals
由 E Rayner‐Hartley 著作 · 2016 · 被引用 59 次 — In summary, ranolazine inhibits the late phase of the inward sodium current in ventricular myocardial cells, which reduces intracellular calcium ... https://www.ahajournals.org Ranolazine: Uses, Interactions, Mechanism of Action - DrugBank
The mechanism of action for ranolazine is not fully understood. At therapeutic concentrations, it can inhibit the cardiac late sodium 205 current (INa), which ... https://go.drugbank.com |