Immune checkpoint activation
A type of drug that blocks proteins called checkpoints that are made by some types of immune system cells, such as T cells, and some cancer cells. ,由 R Zappasodi 著作 · 2018 · 被引用 307 次 — ... facilitate immune activation significantly extends survival of advanced cancer patients. The successes of immune checkpoint blockade, ...
| 相關軟體 Immunet 資訊 | |
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 Immune checkpoint activation 相關參考資料
A guide to cancer immunotherapy: from T cell basic science
由 AD Waldman 著作 · 2020 · 被引用 528 次 — Several evolutionarily conserved negative regulators of T cell activation act as 'checkpoint molecules' to fine-tune the immune response and ... https://www.nature.com Definition of immune checkpoint inhibitor - NCI Dictionary of ...
A type of drug that blocks proteins called checkpoints that are made by some types of immune system cells, such as T cells, and some cancer cells. https://www.cancer.gov Emerging concepts for immune checkpoint blockade-based ...
由 R Zappasodi 著作 · 2018 · 被引用 307 次 — ... facilitate immune activation significantly extends survival of advanced cancer patients. The successes of immune checkpoint blockade, ... https://www.ncbi.nlm.nih.gov Fundamental Mechanisms of Immune Checkpoint Blockade ...
由 SC Wei 著作 · 2018 · 被引用 1296 次 — Immune checkpoint blockade removes inhibitory signals of T-cell activation, which enables tumor-reactive T cells to overcome regulatory ... https://cancerdiscovery.aacrjo Immune checkpoint - Wikipedia
Immune checkpoints are regulators of the immune system. These pathways are crucial for self-tolerance, which prevents the immune system from attacking cells ... https://en.wikipedia.org Immune checkpoint signaling and cancer immunotherapy
由 X He 著作 · 2020 · 被引用 116 次 — Inhibitory functions of immune checkpoints are tightly regulated by surface expression level, receptor-ligand interactions, and intracellular ... https://www.nature.com Immune Checkpoint Signaling Pathway - Creative Diagnostics
https://www.creative-diagnosti Mechanisms of Resistance to Immune Checkpoint Blockade
Although these early hypotheses fueled the field of cancer immunotherapy, better understanding of immune activation, regulation, and interaction with tumor ... https://ascopubs.org Next generation of immune checkpoint therapy in cancer
由 JA Marin-Acevedo 著作 · 2018 · 被引用 398 次 — In cancer, immune checkpoint pathways are often activated to inhibit the nascent anti-tumor immune response. Immune checkpoint therapies act ... https://jhoonline.biomedcentra Novel immune checkpoint targets: moving beyond PD-1 and ...
由 S Qin 著作 · 2019 · 被引用 301 次 — Recent studies have identified several new immune checkpoint targets, like lymphocyte activation gene-3 (LAG-3), T cell immunoglobulin and mucin ... https://molecular-cancer.biome |