Decitabine
由 E Jabbour 著作 · 2008 · 被引用 188 次 — Decitabine (5-aza-2′-deoxycytidine) is a hypomethylating agent with a dual mechanism of action: reactivation of silenced genes and differentiation at low ... ,Drug Type: Decitabine is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. Decitabine is classified as an antimetabolite and a ...
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Decitabine - Wikipedia
Decitabine, sold under the brand name Dacogen, acts as a nucleic acid synthesis inhibitor. ... It is a medication for the treatment of myelodysplastic syndromes, ... https://en.wikipedia.org Evolution of Decitabine Development - NCBI
由 E Jabbour 著作 · 2008 · 被引用 188 次 — Decitabine (5-aza-2′-deoxycytidine) is a hypomethylating agent with a dual mechanism of action: reactivation of silenced genes and differentiation at low ... https://www.ncbi.nlm.nih.gov Decitabine - Drug Information - Chemocare
Drug Type: Decitabine is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. Decitabine is classified as an antimetabolite and a ... https://chemocare.com Decitabine - PubMed
由 B Hackanson 著作 · 2014 · 被引用 37 次 — Besides 5-azacytidine (azacitidine, Vidaza®), 5-aza-2'-deoxycytidine (decitabine, Dacogen®) is the most widely used inhibitor of DNA methylation, ... https://pubmed.ncbi.nlm.nih.go Decitabine: An effective and safe treatment for ... - PubMed
由 X Feng 著作 · 2019 · 被引用 3 次 — However, the application of decitabine in myelodysplastic syndromes (MDSs) and acute myeloid leukemia (AML) has not been fully examined. Thus, our study aimed ... https://pubmed.ncbi.nlm.nih.go Decitabine: Uses, Interactions, Mechanism of Action - DrugBank
Decitabine is a chemotherapeutic pyrimidine nucleoside analogue used for the treatment of myelodysplastic syndromes (MDS) by inducing DNA hypomethylation ... https://go.drugbank.com DACOGEN® (decitabine) for injection, for intravenous use
In preclinical studies in mice and rats, decitabine was teratogenic, fetotoxic, and embryotoxic. If this drug is used during pregnancy, or if a patient becomes ... https://www.accessdata.fda.gov Decitabine (5-Aza-2'-deoxycytidine) | DNMT Inhibitor
Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in ... https://www.medchemexpress.com |